The frequency distribution of lethal chromosomes in finite populations.

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The frequency distribution of lethal chromosomes in finite populations.

The statistical techniques for studying the population dynamics of recessive lethal genes were developed mainly by Wright,'-' who studied the distribution of gene frequencies in populations. In reality, however, the frequencies of individual lethal genes cannot be observed but the frequency of lethal-bearing chromosomes is determined. In large populations the random fluctuation of the frequency...

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Frequency Distribution of Lethal Chromosomes in Small Populations of DROSOPHILA MELANOGASTER.

TUDYING the frequencies and allelic rates of lethal chromosomes in natural populations of Drosophila pseudoobscura, DOBZHANSKY and WRIGHT ( 1941 ) and WRIGHT, DOBZHANSKY and HOVANITZ (1942) showed that the frequency of lethals is much less than would be expected of completely recessive lethals under random mating and this lower frequency is due to either partial inbreeding within populations or...

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The frequency and allelism of lethal chromosomes in isolated desert populations of Drosophila pseudoobscura.

Second-chromosome lethals were extracted from four populations of Drosophila pseudoobscura in Southern California. Two of the populations were from desert oases and two from the classic habitat on Mt. San Jacinto, previously studied by Dobzhansky. Allelism tests were made on the lethals within and between all locations. The frequency of lethal second-chromosomes in each location was 0.18, and t...

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Change in Recessive Lethal Alleles Frequency in Inbred Populations

In a population practicing consanguineous marriage, rare recessive lethal alleles (RRLA) have higher chances of affecting phenotypes. As inbreeding causes more homozygosity and subsequently more deaths, the loss of individuals with RRLA decreases the frequency of these alleles. Although this phenomenon is well studied in general, here some hitherto unstudied cases are presented. An analytical f...

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ژورنال

عنوان ژورنال: Proceedings of the National Academy of Sciences

سال: 1968

ISSN: 0027-8424,1091-6490

DOI: 10.1073/pnas.60.2.517